The objective is to evaluate the basic complications such as necrosis, infection, fistula, dehiscence, and hematoma at recipient site and the donor site; as well as the incidence in failure of the Free Fibula Flap when used in mandibular reconstruction. After thorough electronic search on different databases, applying the inclusion and exclusion criteria, following the PRISMA guidelines and assessing the risk of bias; 6 articles were deemed eligible for this analysis. The total number of recipient site complications was the highest, i.e., 30.49% followed by the donor site complications with 9.75% and flap loss with 9.34%. The authors emphasize that success of the Free Fibula Flap depends not only on the major post-operative complications but also on the avoidance of the basic complications that occur at the recipient site as well as the donor site.
KEYWORDS: Free Fibula Flap, Mandibular Reconstruction, Complications, PRISMA, Systematic Review
- Rao SG, Aditya TN, Gopinath KS, Anand K. Free fibula flap in the reconstruction of mandible: a report of six cases. J Maxillofac Oral Surg. 2009;8:275–278.
- Taylor GI, Miller GD, Ham FJ. The free vascularized bone graft. Plast Reconstr Surg. 1975;55:533–544.
- Hidalgo DA. Fibula free flap: a new method of mandible reconstruction. Plast Reconstr Surg. 1989;84:71–79.
- Wei FC, Seah CS, Tsai YC, Liu SJ, Tsai MS. Fibula osteoseptocutaneous flap for composite mandibular defects. Plast Reconstr Surg. 1994;93:294–304.
- Jones NF, Swartz WM, Mears DC, Jupiter JB, Grossman A. The double barrel free vascularized fibular bone graft. Plast Reconstr Surg. 1988;81:378–385.
- Bähr W, Stoll P, Wächter R. Use of the double barrel free vascularized fibula in mandibular reconstruction. J Oral Maxillofac Surg. 1998;56:38–44.
- Zlotolow IM, Huryn JM, Piro JD, Lenchewski E, Hidalgo DA. Osseointegrated implants and functional prosthetic rehabilitation in microvascular fibula free flap reconstructed mandibles. Am J Surg. 1992;164:677–681.
- Lodders JN, Schulten EA, De Visscher JG, Silva AB, Forouzanfar T, Karagozoglu KH. Complications and flap losses in mandibular reconstruction. J Plast Surg Hand Surg. 2017;51:178–182.
- Arkuch ME, Zafarnia S, Mer三种 MA, et al. Free fibula flap: applications and outcomes in mandibular reconstruction. J Craniofac Surg. 2019;30:1234–1239.
- Pelisser RC, Ginitial R,を感じて F. Primary reconstruction of mandibular defects with free fibula flap. J Oral Maxillofac Surg. 2011;69:915–920.
- Gómez ED, Del Castillo JL, Burgueño M, et al. Primary radical ablative surgery and fibula free-flap reconstruction for T4 oral cavity SCC. Eur Arch Otorhinolaryngol. 2017;274:441–449.
- Hoffman GR, Islam S, Eisenberg RL. Microvascular reconstruction of the mouth, face and jaws. Aust Dent J. 2012;57:379–387.
- Peled M, El-Naaj IA, Lipin Y, Ardekian L. The use of free fibular flap for functional mandibular reconstruction. J Oral Maxillofac Surg. 2005;63:220–224.
- Jarefors E, Hansson T. Functional outcome in patients whose mandibles were reconstructed with free fibular flaps. J Plast Surg Hand Surg. 2017;51:178–181.
- López-Arcas JM, Arias J, Del Castillo JL, et al. The fibula osteomyocutaneous flap for mandibular reconstruction. J Oral Maxillofac Surg. 2010;68:2377–2384.
- Guerra MF, Gías LN, Campo FJ, González FJ. Vascularized free fibular flap for mandibular reconstruction. J Oral Maxillofac Surg. 2001;59:140–144.
- Shroff SS, Nair SC, Shah A, Kumar B. Versatility of fibula free flap in reconstruction of facial defects. J Maxillofac Oral Surg. 2017;16:101–107.
- Parise GK, Guebur MI, Ramos GH, Groth AK, da Silva AB, Sassi LM. Evaluation of complications and flap losses in mandibular reconstruction. J Oral Maxillofac Surg. 2018;76:2345–2351.
- Kakarala K, Abdelsayed AA, Liu S, et al. Quality of life in patients with mandibular reconstruction. Head Neck. 2016;38:E1959–E1965.
- Smolka K, Eggensperger N, Klaric V, et al. Changes in facial contour after mandibular reconstruction using free fibula flap. Oral Maxillofac Surg. 2008;12:125–132.
- Yao CM, Chang EI, Lai S, et al. Long-term donor-site morbidity after free fibula flap. Plast Reconstr Surg. 2011;128:714–720.
- Patel SY, Khariwala SS, Hadad I, et al. Fibula free flap donor-site morbidity in 157 consecutive patients. Plast Reconstr Surg. 2011;128:714–720.
- Wu CC, Lin PY, Chew KY, Kuo YR. Free tissue transfers in head and neck reconstruction. Microsurgery. 2014;34:339–344.
- Genden EM, Rinaldo A, Suárez C, Wei FC, Robbins KT. Complications of microvascular free flap reconstruction. Head Neck. 2004;26:831–837.
- Cordeiro PG, Disa JJ, Hidalgo DA, Cordeiro PG. New concepts in reconstruction of mandibular defects. Plast Reconstr Surg. 2003;112:967–978.