The emergence of PERIOMEDICINE made it explicit that a bidirectional link exists between periodontal diseases and systemic health. For more than 3000years now, this association is being investigated. Starting from the proposal of Focal infection theory, numerous paradigm shifts have been witnessed in the periodontal science. Enormous numbers of research studies supporting the bidirectional link are documented in the literature. However similar amount of evidence against it also exists. This article gives and insight into the various forms of evidence in literature that have been documented to prove an association or causal link or otherwise between periodontal disease and systemic implication.
KEY WORDS: Evidence, Focal infection, Periodontitis, Systemic Health.
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