📚 JIDAM — Open Access Dental Journal|ISSN: 2582-0559|IDA Madras
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Home›Archives›Vol 2, Issue 3 (Jul–Sep 2014)›Article 003
JIDAM · Vol 2, Issue 3 · July–September 2014
Review

Low intensity pulsed ultrasound in periodontal regeneration

S.Gopalakrishnan, Parthiban Saket, V.Shankarram
Thai Moogambigai Dental College and Hospital, Mugappair, Chennai
Vol 2 · Issue 3 · 2014 DOI: 10.37841/jidam.2014.v2.i3.003 🔓 Open Access 📅 2014
3
Authors
36
References
2014
Year Published
📝Abstract

Dental caries and periodontal diseases are the two most diseases of the oral cavity. Not only do they present physical and social hazards but also seriously compromise human health and quality of life. Tissue engineering has contributed to the cessation of many oral diseases. Several methods have been described to enhance cellular performance and low intensity pulsed ultrasound (LIPUS) has shown to play an important role in cell metabolism. LIPUS stimulation is a classical therapeutic modality for bone regeneration and its efciency has been widely reported over the years. Interestingly, recent studies have provided evidence that LIPUS plays an important role in the metabolism of periodontal cells and tissues as well. Normal bone physiology is known to be regulated by mechanical stimulation. Both osteoblastic and osteoclastic activity have been proved to be mediated by mechanical stimuli. Osteoclasts initiate bone resorption in response to determined signals and osteoblasts are recruited to deposit bone matrix in response to a coupling signal. Osteoclast and osteoblast activity could thus be related to opposite strain modalities. During orthodontic tooth movement, for example, the networked reactions that occur in and around periodontal ligament and alveolar bone cells change compressive and tensile stresses into molecular events, resulting in bone resorption and formation, respectively. Other types of mechanical stimulation could thus modify cell metabolism, including ultrasound. LIPUS (intensity ranging from 30 - 100 mW/cm2) is an acoustic radiation that can be transmitted into the living tissues as pressure waves resulting in biochemical events at the cellular level. LIPUS has been shown to stimulate bone and cartilage cells in vitro, indicating that ultrasound exerts direct anabolic effects such as production of growth factors and other signaling molecules, osteogenic differentiation and extra cellular matrix production. The mechanisms involved in LIPUS-stimulated tissue repair is by the anabolic biophysical effects caused by mechanical stress and uid micro-streaming which has an impact on the cellular plasma membrane. This triggers a cascade of intracellular signal transduction which in turn causes a subsequent gene transcription.

🔖How to Cite
Gopalakrishnan S, Saket P, Shankarram V. Low intensity pulsed ultrasound in periodontal regeneration. J Indian Dent Assoc Madras. 2014;2(3). DOI: 10.37841/jidam.2014.v2.i3.003
Gopalakrishnan, S., Saket, P., & Shankarram, V. (2014). Low intensity pulsed ultrasound in periodontal regeneration. Journal of Indian Dental Association Madras, 2(3). https://doi.org/10.37841/jidam.2014.v2.i3.003
Gopalakrishnan, S., et al. "Low intensity pulsed ultrasound in periodontal regeneration." Journal of Indian Dental Association Madras, vol. 2, no. 3, 2014. DOI: 10.37841/jidam.2014.v2.i3.003.
Gopalakrishnan S, Saket P, Shankarram V. Low intensity pulsed ultrasound in periodontal regeneration. J Indian Dent Assoc Madras. 2014;2(3). doi:10.37841/jidam.2014.v2.i3.003
Gopalakrishnan, S., Parthiban Saket, and V. Shankarram. "Low intensity pulsed ultrasound in periodontal regeneration." Journal of Indian Dental Association Madras 2, no. 3 (2014). https://doi.org/10.37841/jidam.2014.v2.i3.003.
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