Clinical Aspects of Regenerative Endodontic Procedures - A Review

The concept of regenerative endodontics has gained much attention in endodontics in the past decade. The endodontic management of permanent immature teeth remains with challenges. Although treatment modalities for vital pulp therapy in these teeth provide long-term favorable outcome, the treatment of teeth with pulpal necrosis and apical periodontitis are signicantly less predictable. Immature teeth diagnosed with pulpal necrosis have been traditionally treated with apexication or apexogenesis approaches. Unfortunately, these procedures provide little to no benet in attaining continued root development. Regenerative endodontic procedures have evolved as an important alternative in treating teeth with otherwise questionable long-term prognosis because of thin, fragile dentinal walls. These procedures rely heavily on chemical disinfection of the root canal system. This review summarizes the current literature supporting a biological rationale for considering regenerative endodontic treatment procedures in treating the immature permanent tooth with pulpal necrosis.

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